WIF1, WNT inhibitory factor 1, 11197

N. diseases: 171; N. variants: 1
Disease: Familial multiple trichoepitheliomata ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1275122
Disease: Familial multiple trichoepitheliomata
Familial multiple trichoepitheliomata 		0.030 AlteredExpression disease BEFREE The kappa consistency coefficient was ‑0.369 between methylation and mRNA expression (P<0.05) and WIF1 expression levels were significantly downregulated in EAC tissues compared with non‑tumorous tissues (P<0.01). 28944908 2017
CUI: C1275122
Disease: Familial multiple trichoepitheliomata
Familial multiple trichoepitheliomata 		0.030 Biomarker disease BEFREE Moreover, seven of them (ADAMTS18, APC, DKK2, FOXL2, GPX3, TIMP3 and WIF1) were found aberrantly methylated in all or almost all the tumor samples, suggesting an important role for these genes in EAC. 27634218 2016
CUI: C1275122
Disease: Familial multiple trichoepitheliomata
Familial multiple trichoepitheliomata 		0.030 Biomarker disease BEFREE Restoration of WIF-1 could sensitize the EAC cells to the chemotherapy drug cisplatin. 18005197 2008