CHEK2, checkpoint kinase 2, 11200

N. diseases: 297; N. variants: 261
Disease: Carcinoma, Lobular ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0206692
Disease: Carcinoma, Lobular
Carcinoma, Lobular 		0.010 GeneticVariation disease LHGDN There was no significant overall association between CHEK2 and breast cancer (OR = 1.3; p = 0.30), but among those with lobular carcinoma the association with the I157T missense mutation was very strong (OR = 6.6; p > 0.0001). 15803365 2005
CUI: C0206692
Disease: Carcinoma, Lobular
Carcinoma, Lobular 		0.010 GeneticVariation disease BEFREE There was no significant overall association between CHEK2 and breast cancer (OR = 1.3; p = 0.30), but among those with lobular carcinoma the association with the I157T missense mutation was very strong (OR = 6.6; p > 0.0001). 15803365 2005