CHEK2, checkpoint kinase 2, 11200

N. diseases: 297; N. variants: 261
Disease: Multiple malignancy ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0346429
Disease: Multiple malignancy
Multiple malignancy 		0.010 GeneticVariation phenotype BEFREE Germline mutations in checkpoint kinase 2 (CHEK2), a multiple cancer-predisposing gene, increase breast cancer (BC) risk; however, risk estimates differ substantially in published studies. 31050813 2019