CHEK2, checkpoint kinase 2, 11200

N. diseases: 297; N. variants: 261
Disease: Carcinoma of larynx ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0595989
Disease: Carcinoma of larynx
Carcinoma of larynx 		0.010 GeneticVariation disease BEFREE The presence of a CHEK2 mutation was protective against both lung cancer [odds ratio (OR) = 0.3; 95% confidence interval (CI) 0.2-0.5; P = 3 x 10(-8)] and laryngeal cancer (OR = 0.6; 95% CI 0.3-0.99; P = 0.05). 18281249 2008