IL17F, interleukin 17F, 112744

N. diseases: 236; N. variants: 10
Disease: Carcinogenesis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.050 Biomarker phenotype BEFREE Furthermore, the data suggest that the increase of IL-17A and IL-17F in Th17 cells, derived from CD4<sup>+</sup> T cells, reflects the chronic inflammation in gastric mucosa, whereas the absence of change of IL-17A and decrease of IL-17F in CD8<sup>+</sup>Tc17 cells suggest loss of cytotoxic function of CD8<sup>+</sup>Tc17 cells during gastric tumorigenesis of the <i>Tff1</i>-KO mice. 28900479 2017
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.050 GeneticVariation phenotype BEFREE Role of IL-17F T7488C polymorphism in carcinogenesis: a meta-analysis. 24913709 2014
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.050 AlteredExpression phenotype BEFREE Interleukin IL-17F was expressed in colon epithelial cells and showed multiple functions in colon tumorigenesis. 24423465 2014
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.050 Biomarker phenotype BEFREE These results indicate that IL-17F plays an inhibitory role in colon tumorigenesis in vivo. 22509371 2012
CUI: C0596263
Disease: Carcinogenesis
Carcinogenesis 		0.050 Biomarker phenotype BEFREE Conversely, downstream of IL-17R binding, IL-17A and IL-17F induce key signal transduction pathways implicated in inflammation and carcinogenesis. 17644350 2007