TREX1, three prime repair exonuclease 1, 11277

N. diseases: 241; N. variants: 36
Disease: Cerebrovascular accident ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.130 Biomarker group BEFREE The number of TREX1<sup>+</sup> microglia was increased in ischemic brain lesions in central nervous system of RVCL and stroke patients. 30062819 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.130 GeneticVariation group BEFREE Here we confirm the causative role played by TREX1 autosomal dominant fs mutations disrupting the C-terminal of the protein, providing a model for the study of stroke in young adults. 25213617 2015
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.130 GeneticVariation group BEFREE The main hereditary vascular conditions involving both retinal and cerebral vessels include cerebroretinal vasculopathy, HERNS (hereditary endotheliopathy with retinopathy, nephropathy, and stroke), and hereditary vascular retinopathy; all are linked to the same locus on chromosome 3p21. 12525718 2003
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident 		0.130 Biomarker group HPO