TREX1, three prime repair exonuclease 1, 11277

N. diseases: 241; N. variants: 36
Disease: Sjogren's Syndrome ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.020 GeneticVariation disease BEFREE TREX1 variants in Sjogren's syndrome related lymphomagenesis. 31326279 2019
CUI: C1527336
Disease: Sjogren's Syndrome
Sjogren's Syndrome 		0.020 Biomarker disease BEFREE We performed a mutational analysis of the TREX1 gene on three autoimmune diseases: SLE (210 patients) and SS (58 patients), to confirm a TREX1 involvement in the Italian population, and systemic sclerosis (SSc, 150 patients) because it shares similarities with SLE (presence of antinuclear antibodies and connective tissue damage). 24224166 2013