CHRM1, cholinergic receptor muscarinic 1, 1128

N. diseases: 68; N. variants: 2
Disease: Amnesia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0002622
Disease: Amnesia
Amnesia 		0.010 Biomarker disease BEFREE Thus, enhancing hippocampal muscarinic signaling using M1 mAChR PAMs restored memory loss and slowed the progression of mouse prion disease, indicating that this ligand type may have clinical benefit in diseases showing defective cholinergic transmission, such as AD. 27991860 2017