CHRM1, cholinergic receptor muscarinic 1, 1128

N. diseases: 68; N. variants: 2
Disease: Prion Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0162534
Disease: Prion Diseases
Prion Diseases 		0.010 GeneticVariation group BEFREE The memory deficits we observed in mouse prion disease were completely restored by treatment with benzyl quinolone carboxylic acid (BQCA) and benzoquinazoline-12 (BQZ-12), two highly selective positive allosteric modulators (PAMs) of M1 mAChRs. 27991860 2017