LYST, lysosomal trafficking regulator, 1130

N. diseases: 114; N. variants: 18
Disease: Atrial Fibrillation ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.020 GeneticVariation disease BEFREE In the CHS, multivariable analyses revealed that a baseline 12-lead ECG premature atrial contraction predicted a 60% increased risk of atrial fibrillation (hazard ratio, 1.6; 95% CI, 1.3-2.0; <i>P</i><0.001) and a premature ventricular contraction predicted a 30% increased risk of heart failure (hazard ratio, 1.3; 95% CI, 1.0-1.6; <i>P</i>=0.021). 28775064 2017
CUI: C0004238
Disease: Atrial Fibrillation
Atrial Fibrillation 		0.020 GeneticVariation disease BEFREE In meta-analyses of prospectively followed ARIC and CHS participants (n = 3,656), rs7629265 was associated with increased AF risk (n = 299 AF cases; HR = 1.74, P = 1.9 × 10(-4) ). 25065297 2014