|
Anaplastic thyroid carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
Intensity of BLI signals in ATC lung metastasis was weaker in the clodro-lipo group than PBS-lipo control.
|
27537102 |
2016 |
|
ANOPHTHALMIA AND PULMONARY HYPOPLASIA
|
0.010 |
Biomarker
|
disease |
BEFREE |
<b>Abbreviations</b>: CDH1: cadherin 1; CDH2: cadherin 2; CI: combination index; CQ: chloroquine; DFS: disease-free survival; EMT: epithelial-to-mesenchymal transition; ERK: extracellular signal-regulated protein kinase; GFP: green fluorescent protein; IHC: immunohistochemistry; MAP1LC3B/LC3B: microtubule associated protein 1 light chain 3 beta; MAPK: mitogen-activated protein kinase; OS: overall survival; PBS: phosphate-buffered saline; PDAC: pancreatic ductal adenocarcinoma; RAP: rapamycin; RFP: red fluorescent protein; RT: room temperature; shRNA: short-hairpin RNA; SQSTM1: sequestosome 1; TCGA: The Cancer Genome Atlas; TEM: transmission electron microscopy; TGFB1: transforming growth factor beta 1; TMA: tissue microarray.
|
31177911 |
2020 |
|
Anus, Imperforate
|
0.100 |
Biomarker
|
disease |
HPO |
|
|
|
|
Anxiety
|
0.010 |
Biomarker
|
disease |
BEFREE |
These results alert that the PBS might be a sign of stress and other psychological problems such as tension and anxiety related to the presence of harmful oral habits.
|
31286259 |
2020 |
|
Anxiety Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
These results alert that the PBS might be a sign of stress and other psychological problems such as tension and anxiety related to the presence of harmful oral habits.
|
31286259 |
2020 |
|
Aplasia of the abdominal wall musculature
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Aplasia/Hypoplasia of the lungs
|
0.100 |
Biomarker
|
phenotype |
HPO |
|
|
|
|
Arteriosclerosis
|
0.040 |
Biomarker
|
disease |
BEFREE |
In the present study, atherosclerosis was significantly enhanced in high-cholesterol diet (HCD)-fed New Zealand white rabbits immunized with mHSP65(91-105) compared with PBS-immunized or BSA-immunized rabbits.
|
22038107 |
2012 |
|
Arteriosclerosis
|
0.040 |
Biomarker
|
disease |
BEFREE |
The rats with atherosclerosis received continuous drug or PBS administration via intravenous injection for a treatment period of 30 days, following which all animals were sacrificed.
|
29257234 |
2018 |
|
Arteriosclerosis
|
0.040 |
Biomarker
|
disease |
BEFREE |
In addition, L. plantarum ZDY04 can significantly inhibit the development of TMAO-induced atherosclerosis in ApoE-/- 1.3% choline-fed mice as compared with the untreated PBS group.
|
30039147 |
2018 |
|
Arteriosclerosis
|
0.040 |
Biomarker
|
disease |
BEFREE |
Four experimental groups were constructed: an untreated HC group; an untreated AS group injected with PBS; a null EPC AS group injected with null vector-transduced EPCs, and an hTERT EPC AS group injected with hTERT-transduced EPCs.
|
27825159 |
2018 |
|
Arthritis
|
0.020 |
GeneticVariation
|
disease |
BEFREE |
Fifty healthy male Sprague Dawley rats were divided into three groups: group I (n = 10), negative control; group II (n = 20), positive control (induction of arthritis by adjuvant followed by intravenous injection of 0.1 ml of PBS); and group III (n = 20), intervention (as for group II but injected intravenously with 1 × 10<sup>6 </sup> cells ml<sup>-1</sup> of BMMSCs suspended in PBS).
|
29952027 |
2018 |
|
Arthritis
|
0.020 |
Biomarker
|
disease |
BEFREE |
The effects of two injections of Ad.hIL-1Ra/GFP or control virus with no inserted target gene (Ad.GFP) were compared with the effects of PBS injection with respect to the clinical characteristics of arthritis, as determined by articular index scores, histopathological and immunological assays.
|
16793145 |
2006 |
|
Ascites
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Only AOM-treated Chrm3(-/-) mice developed ascites and had reduced survival compared with AOM-treated wild-type controls.
|
20197374 |
2010 |
|
Asthma
|
0.070 |
Biomarker
|
disease |
BEFREE |
We highlight targets for drugs and compounds in development for COPD and asthma (genes in the inositol phosphate metabolism pathway and CHRM3) and describe targets for potential drug repositioning from other clinical indications.
|
28166213 |
2017 |
|
Asthma
|
0.070 |
GeneticVariation
|
disease |
LHGDN |
We considered the cholinergic receptor muscarinic 3 gene as a possible candidate gene for bronchial asthma and initiated studies to identify polymorphisms in the promoter region.
|
12642833 |
2003 |
|
Asthma
|
0.070 |
Biomarker
|
disease |
BEFREE |
Features of asthma were either marginal or absent in OVA-treated pups of PBS-exposed mice.
|
24365139 |
2014 |
|
Asthma
|
0.070 |
Biomarker
|
disease |
BEFREE |
To determine whether single nucleotide polymorphisms (SNPs) or haplotypes in CHRM1, CHRM2, or CHRM3 are associated with asthma in Mexican pediatric population.
|
24430298 |
2014 |
|
Asthma
|
0.070 |
Biomarker
|
disease |
BEFREE |
Neonates of mothers exposed to TiO(2) (and DEP, but not PBS) developed AHR and AI, indicating that pregnancy exposure to both "inert" TiO(2) and DEP caused increased asthma susceptibility in offspring.
|
17656681 |
2008 |
|
Asthma
|
0.070 |
Biomarker
|
disease |
BEFREE |
We considered the cholinergic receptor muscarinic 3 gene as a possible candidate gene for bronchial asthma and initiated studies to identify polymorphisms in the promoter region.
|
12642833 |
2003 |
|
Asthma
|
0.070 |
AlteredExpression
|
disease |
BEFREE |
The aim of this study was to evaluate the β2-adrenoceptor (ADRB2) and M3-cholinoreceptor (CHRM3) gene expression in bronchial mucosa in patients with COPD and different severity of asthma.
|
22192964 |
2012 |
|
Asthma
|
0.070 |
Biomarker
|
disease |
BEFREE |
Mice on a GAFD sensitized with PBS did not develop AHR after local provocation with methacholine.
|
29600329 |
2019 |
|
Atherosclerosis
|
0.040 |
Biomarker
|
disease |
BEFREE |
In addition, L. plantarum ZDY04 can significantly inhibit the development of TMAO-induced atherosclerosis in ApoE-/- 1.3% choline-fed mice as compared with the untreated PBS group.
|
30039147 |
2018 |
|
Atherosclerosis
|
0.040 |
Biomarker
|
disease |
BEFREE |
In the present study, atherosclerosis was significantly enhanced in high-cholesterol diet (HCD)-fed New Zealand white rabbits immunized with mHSP65(91-105) compared with PBS-immunized or BSA-immunized rabbits.
|
22038107 |
2012 |
|
Atherosclerosis
|
0.040 |
Biomarker
|
disease |
BEFREE |
The rats with atherosclerosis received continuous drug or PBS administration via intravenous injection for a treatment period of 30 days, following which all animals were sacrificed.
|
29257234 |
2018 |