CHRM4, cholinergic receptor muscarinic 4, 1132

N. diseases: 27; N. variants: 0
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker disease PSYGENET These findings led us to determine whether variation in the CHRM4 gene sequence was associated with an altered risk of schizophrenia by sequencing the CHRM4 gene from the brains of 76 people with the disorder and 74 people with no history of psychiatric disorders. 23490763 2013
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.360 Biomarker disease PSYGENET Genetic variation in a region on chromosome 11 that contains the candidate genes AMBRA1, DGKZ, CHRM4 and MDK was significantly associated with SCZ in the combined sample (n=11 540; P=3.89 × 10(-9), odds ratio (OR)=1.25). 21747397 2012
CUI: C0007398
Disease: Catatonia
Catatonia 		0.300 Therapeutic disease CTD_human Effect of M4-cholinoceptor blockade on haloperidol-produced catatonic syndrome in rats. 15273762 2004
CUI: C0338650
Disease: Catatonia, Organic
Catatonia, Organic 		0.300 Therapeutic phenotype CTD_human Effect of M4-cholinoceptor blockade on haloperidol-produced catatonic syndrome in rats. 15273762 2004
CUI: C0750992
Disease: Catatonia, Malignant
Catatonia, Malignant 		0.300 Therapeutic disease CTD_human Effect of M4-cholinoceptor blockade on haloperidol-produced catatonic syndrome in rats. 15273762 2004
CUI: C0750993
Disease: Schizophreniform Catatonia
Schizophreniform Catatonia 		0.300 Therapeutic phenotype CTD_human Effect of M4-cholinoceptor blockade on haloperidol-produced catatonic syndrome in rats. 15273762 2004
CUI: C0040822
Disease: Tremor
Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0040827
Disease: Saturnine Tremor
Saturnine Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0149840
Disease: Senile Tremor
Senile Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234370
Disease: Persistent Tremor
Persistent Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234371
Disease: Continuous Tremor
Continuous Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234372
Disease: Intermittent Tremor
Intermittent Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234373
Disease: Fine Tremor
Fine Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234374
Disease: Coarse Tremor
Coarse Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234375
Disease: Massive Tremor
Massive Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234376
Disease: Action Tremor
Action Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234377
Disease: Passive Tremor
Passive Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234378
Disease: Static Tremor
Static Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234379
Disease: Resting Tremor
Resting Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0234381
Disease: Darkness Tremor
Darkness Tremor 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0235078
Disease: Tremor, Perioral
Tremor, Perioral 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0235081
Disease: Tremor, Limb
Tremor, Limb 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0235082
Disease: Tremor, Muscle
Tremor, Muscle 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0235083
Disease: Nerve Tremors
Nerve Tremors 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999
CUI: C0235843
Disease: Tremor, Neonatal
Tremor, Neonatal 		0.300 Biomarker phenotype CTD_human Characterization of the muscarinic receptor subtype mediating pilocarpine-induced tremulous jaw movements in rats. 9920179 1999