CBX3, chromobox 3, 11335

N. diseases: 53; N. variants: 0
Disease: High-Grade Prostatic Intraepithelial Neoplasia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1168327
Disease: High-Grade Prostatic Intraepithelial Neoplasia
High-Grade Prostatic Intraepithelial Neoplasia 		0.010 AlteredExpression disease BEFREE In tissue arrays, quantitative imaging detects increased GLB1 expression in high-grade prostatic intraepithelial neoplasia (HGPIN), known to contain senescent cells, and cancer compared to benign prostate tissues (p<0.01) and senescent cells contain low Ki67 and elevated HP1γ. 25876105 2015