MGLL, monoglyceride lipase, 11343

N. diseases: 125; N. variants: 7
Disease: Drug Dependence ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1510472
Disease: Drug Dependence
Drug Dependence 		0.020 GeneticVariation group BEFREE Dysfunction of monoacylglycerol lipase (MAGL) is associated with several psychopathological disorders, including drug addiction and neurodegenerative diseases. 31518130 2019
CUI: C1510472
Disease: Drug Dependence
Drug Dependence 		0.020 AlteredExpression group BEFREE Blockade of MAGL increases 2-AG levels, resulting in subsequent activation of the endocannabinoid system, and has emerged as a novel therapeutic strategy to treat drug addiction, inflammation, and neurodegenerative diseases. 29481079 2018