|
Colitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Polysaccharide from Scutellaria baicalensis Georgi ameliorates colitis via suppressing NF-κB signaling and NLRP3 inflammasome activation.
|
30936012 |
2019 |
|
Colitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
In summary, the AMPK-NLRP3-IL-1β signaling axis plays an important role in colitis following WEL treatments.
|
28750357 |
2017 |
|
Colitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
NLRP3 inflammasome has a protective effect against oxazolone-induced colitis: a possible role in ulcerative colitis.
|
27966619 |
2016 |
|
Colitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
ZBEO also inhibited NLRP3 activation in colitis in mice.
|
28368613 |
2017 |
|
Colitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Emerging evidence suggests that NLRP3 inflammasome provides a link between colitis-associated colorectal cancer and inflammatory bowel diseases.
|
29296531 |
2017 |
|
Colitis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Mechanistically, enhanced NLRP3 inflammasome expression with elevated IL-1β was a predominant feature during the initiation of colitis with miR-223 deficiency.
|
28487310 |
2017 |
|
Colitis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We investigated the effects of TiO<sub>2</sub> in the development of colitis and the role of the nucleotide-binding oligomerisation domain receptor, pyrin domain containing (NLRP)3 inflammasome.
|
26848183 |
2017 |
|
Colitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
NLRP3 inflammasome has been reported to be associated with inflammatory bowel disease including colitis due to its potential ability to induce IL-1β secretion.
|
30901677 |
2019 |
|
Colitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Angiotensin converting enzyme (ACE) inhibitors and AII Receptor Antagonists (ARBs) are therapeutic in animal models of colitis.
|
27014752 |
2016 |
|
Colitis
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
However, the protection of VI-16 against DSS-induced colitis was dependent on NLRP3 expression in hematopoietic cells.
|
31152156 |
2019 |
|
Colitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
NLRP3 inflammasome has been reported to be associated with various kinds of immunological diseases including colitis.
|
23506741 |
2013 |
|
Colitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our results indicate that CA could ameliorate DSS-induced colitis through inhibition of NLRP3 inflammasome activation and miR-21 and miR-155 levels in colons and macrophage, suggesting that CA might be a potentially effective drug for UC.
|
30530166 |
2019 |
|
Colitis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Although the exact aetiology of IBD is unknown, uncontrolled NLRP3 Inflammasome activation has shown to play a major role in the chronic intestinal inflammation and mature IL-1β and IL18 are consistently associated with increased colitis and colitis associated colorectal cancer development.
|
28155620 |
2017 |