NLRP3, NLR family pyrin domain containing 3, 114548

N. diseases: 805; N. variants: 74
Disease: Immune System Diseases ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021053
Disease: Immune System Diseases
Immune System Diseases 		0.050 Biomarker group BEFREE Understanding the cellular and molecular biology of the NLRP3 inflammasome is necessary because the NLRP3 inflammasome may be a potential therapeutic target for the treatment and prevention of oral inflammatory and immunological diseases. 30315987 2019
CUI: C0021053
Disease: Immune System Diseases
Immune System Diseases 		0.050 Biomarker group BEFREE Emerging evidence suggests that NLRP3 inflammasome was associated with various kinds of immunological diseases including colitis. 31152156 2019
CUI: C0021053
Disease: Immune System Diseases
Immune System Diseases 		0.050 Biomarker group BEFREE The NLRP3 inflammasome plays a key role in the inflammation process, and its aberrant activation leads to several inflammatory or immune diseases. 29558930 2018
CUI: C0021053
Disease: Immune System Diseases
Immune System Diseases 		0.050 Biomarker group BEFREE NLRP3 inflammasome has been reported to be associated with various kinds of immunological diseases including colitis. 23506741 2013
CUI: C0021053
Disease: Immune System Diseases
Immune System Diseases 		0.050 GeneticVariation group BEFREE Disease-associated SNPs (5 in NLRP1 and 2 in NLRP3), previously associated to infections and to immunologic disorders, were genotyped in 467 leprosy patients (327 multibacillary, MB; 96 paucibacillary, PB) and in 380 healthy controls (HC) from the state of Sao Paulo (Brazil), and in 183 patients (147MB; 64PB) and 186 HC from Mato Grosso (Brazil). 23770116 2013