Disease: Sepsis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0243026
Disease: Sepsis
Sepsis 		0.040 Biomarker disease BEFREE These findings verify the ability of gefitinib to directly disrupt the interaction of TIRAP and c-Jun, thereby inhibiting a major inflammatory response that is often observed in patients experiencing sepsis. 30909134 2019
CUI: C0243026
Disease: Sepsis
Sepsis 		0.040 GeneticVariation disease BEFREE Genetic variants in the TIRAP gene are associated with increased risk of sepsis-associated acute lung injury. 21118491 2010
CUI: C0243026
Disease: Sepsis
Sepsis 		0.040 Biomarker disease BEFREE Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts. 20525286 2010
CUI: C0243026
Disease: Sepsis
Sepsis 		0.040 GeneticVariation disease BEFREE Remarkably, homozygous TIRAP 180L tend to increase the risk of sepsis in the German study (P = 0.04). 19602285 2009