H3P47, H3 histone pseudogene 47, 115482706

N. diseases: 65; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.050 Biomarker disease BEFREE The present study aimed to investigate whether p57 can enhance the sensitivity of HCC cells to Erlotinib (Er)/Cetuximab(C-225) and further explore the potential mechanisms of Er/C-225 resistance. 30178471 2019
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.050 Biomarker disease BEFREE Cytoplasmic p57 might be a key regulator in hepatocellular carcinoma invasion via the LIM domain kinase 1/p-cofilin pathway. 26271467 2015
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.050 AlteredExpression disease BEFREE The downregulation of RFC3 expression led to HCC cell cycle arrest in the S phase, partly by regulating the epression of cell cycle-related proteins, such as p21, p53, p57 and cyclin A. 26397132 2015
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.050 Biomarker disease BEFREE Multivariate analysis showed that tumor size, TNM stage, p57, RhoA and combined loss of p57 with RhoA were risk factors for poor survival of HCC patients. 23842948 2013
CUI: C2239176
Disease: Liver carcinoma
Liver carcinoma
0.050 Biomarker disease BEFREE Based on these findings, p57 may be a potential target for HCC prevention and therapy. 22002319 2011