H3P10, H3 histone pseudogene 10, 115482713

N. diseases: 769; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE Association between oropharyngeal cancers with known HPV and p16 status and cervical intraepithelial neoplasia: a Danish population-based study. 30626248 2019
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE The search included published studies which dealt with detection methods of HPV-related oral and oropharyngeal cancers and biomolecular studies, particularly regarding the compromising of p53 p16 and e-cadherin’s. 29460521 2019
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 AlteredExpression disease BEFREE Definitive radiochemotherapy or initial surgery for oropharyngeal cancer : To what extent can p16 expression be used in the decision process? 30877351 2019
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 GeneticVariation disease BEFREE Patients with OPC with available p16 status and tobacco history were eligible. 30913305 2019
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE Our findings support the hypothesis that p16 has a similar prognostic role in both nonoropharyngeal and oropharyngeal cancer. 29878161 2018
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 AlteredExpression disease BEFREE Oropharynx cancer with significant p16 expression showed an increased overall survival and elevated T- and B-lymphocyte infiltration, which suggests a prognostic relevance of immune cell infiltration. 29493423 2018
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE Relationship Between p16 Expression and Prognosis in Patients with Oropharyngeal Cancer Undergoing Surgery. 29936482 2018
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE Evaluate the prognostic and predictive impact of HPV-associated p16-expression and assess the combined prognostic impact of p16 and smoking on altered fractionated radiotherapy (AFRT) for oropharyngeal cancer (OPC) within the frames of the update of the Meta-Analysis of Radiotherapy in Carcinomas of Head and neck (MARCH). 29100700 2018
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE Our study investigates the prevalence, prognostic, and clinicopathologic features of HPV-related oropharyngeal cancer in Northeast China and elucidates the involvement of p16 in the tumorigenesis and progression of OPSCC. 30310820 2018
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE The HPV values for Iowa patients with oropharyngeal cancers (n = 824) were recoded based on modified guidelines that included p16 test results, and compared with the original guidelines. 29934978 2018
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE Clinical outcomes and prognostic factors in cisplatin versus cetuximab chemoradiation for locally advanced p16 positive oropharyngeal carcinoma. 29598954 2018
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 AlteredExpression disease BEFREE HPV infection and P16 expression in oral and oropharyngeal cancer in Kazakhstan. 29344081 2018
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE The study subset with OPC and known p16 status was mainly from Australasia, Western Europe, and North America. 27209505 2017
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE HPV16 was searched in 255 LA-HNC formalin-fixed paraffin-embedded tumor tissues, 89 oropharyngeal cancers (OPCs), and 166 non-OPCs by DNA-PCR with 3 primer pairs. p16 was analyzed by immunohistochemistry in 235 patients. 27040135 2017
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE Immunohistochemistry for p16 is established as a surrogate marker of human papillomavirus (HPV) in oropharyngeal cancer. p16 expression in HNcSCC needs to be elucidated to determine its utility in predicting the primary site. 28663082 2017
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 AlteredExpression disease BEFREE Objectives We analyze the relationship between CD44, epidermal growth factor receptor (EGFR), and p16 expression in oral cavity and oropharyngeal cancers in a diverse population. 28397583 2017
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE We sought to investigate the pathology and rates of HPV head and neck oropharyngeal cancer in Japan via p16 immunohistochemistry at 2 institutions in Japan. 27913709 2017
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE Patients with oropharyngeal carcinoma positive for human papillomavirus or p16 lived longer after locoregional failure compared with patents with oropharyngeal carcinoma negative for human papillomavirus or p16 (median survival, 36.5 vs 13.6 months; P = .007) but not after distant metastasis. 28542679 2017
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE The pretreatment QOL/PS scores were correlated with outcome and p16 status in patients with oropharyngeal cancer (OPC). 27727066 2017
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE Tumor p16 status was evaluable in 182 patients with OPC enrolled in the IMCL-9815 study; 41% were p16 positive. 26712222 2016
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 AlteredExpression disease BEFREE No benefit for regional control and survival by planned neck dissection in primary irradiated oropharyngeal cancer irrespective of p16 expression. 26059208 2016
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 AlteredExpression disease BEFREE Impact of p16 expression in oropharyngeal cancer in the postoperative setting: the necessity of re-evaluating traditional risk stratification. 27474125 2016
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE The diagnosis of HPV-related oropharyngeal cancer in clinical practice is based on p16 immunohistochemistry and PCR detection of viral DNA (HPV-PCR). 25687724 2015
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE Population-based p16 and HPV positivity rates in oropharyngeal cancer in Southeast Scotland. 26152733 2015
CUI: C2349952
Disease: Oropharyngeal Carcinoma
Oropharyngeal Carcinoma
0.100 Biomarker disease BEFREE We performed immunohistochemistry for the p16 protein, in situ hybridization for human papillomavirus-deoxyribonucleic acid and polymerase chain reaction for the human papillomavirus-deoxyribonucleic acid oncogene E6 in oropharyngeal carcinoma in Japanese patients. 26056326 2015