ADD1, adducin 1, 118

N. diseases: 67; N. variants: 11
Disease: Gastroschisis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0265706
Disease: Gastroschisis
Gastroschisis 		0.020 GeneticVariation disease BEFREE The rs4961 (ADD1), rs5443 (GNB3), rs1042713, and rs1042714 (ADRB2) were significantly associated with gastroschisis. 29550988 2018
CUI: C0265706
Disease: Gastroschisis
Gastroschisis 		0.020 GeneticVariation disease BEFREE In logistic regression, controlling for maternal ethnicity, and using the homozygote wild-type as referent, the following gene polymorphisms were associated with an increased risk for a gastroschisis for heterozygotes: ICAM1 gly241arg (odds ratio [OR], 1.9; 95% confidence interval [CI], 1.1 -3.4); NOS3 glu298asp (OR, 1.9; 95% CI, 1.1-3.4); NPPA 2238T > C (OR, 1.9; 95% CI, 1.0-3.4); and ADD1 gly460trp (OR, 1.5; 95% CI, 0.8-2.8). 17051589 2006