|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
Although some mucins are membrane bound, our data indicate that MUCL1 is secreted by some breast cancer cells, whereas others only express high levels of intracellular MUCL1.
|
26725324 |
2016 |
|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
GCDFP15, MGB1, and SBEM were the most sensitive and specific markers to detect BC metastatic cells when at least one was expressed by quantitative RT-PCR.
|
26364839 |
2015 |
|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
SBEM has the potential to be a specific marker for predicting hematogenous micrometastasis and response to neoadjuvant chemotherapy in breast cancer.
|
20364301 |
2010 |
|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
In invasive carcinoma patients, several cellular and extracellular proteins that were significantly increased (Periostin, Small breast epithelial mucin) or decreased (Kinectin) have previously been associated with breast cancer, thereby supporting this approach for a larger disease-stage characterization effort.
|
20560667 |
2010 |
|
Malignant neoplasm of breast
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
SBEM mRNA status and time to breast cancer progression were analysed using Kaplan-Meyer curves.
|
19221791 |
2009 |
|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
SBEM tag was detected in 40 libraries (21 BC; 8 non-cancerous breast tissues).
|
18497056 |
2008 |
|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
Our results suggest that SBEM may identify a unique subset of breast cancers with poor prognosis and may have future implications for therapeutic management of this disease.
|
18269587 |
2008 |
|
Malignant neoplasm of breast
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Genes such as MGA, B726P and SBEM that are expressed relatively exclusively in breast tissue are potential new markers for breast cancer.
|
18253069 |
2007 |
|
Malignant neoplasm of breast
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Clarifying the SBEM gene regulation will help to dissect mechanisms underlying transcription of normal breast and breast cancer-associated genes.
|
16720387 |
2006 |
|
Malignant neoplasm of breast
|
0.100 |
Biomarker
|
disease |
BEFREE |
We selected three molecules, small breast epithelial mucin (SBEM), prostate epithelium-specific Ets transcription factor (PDEF), and mammaglobin (MGB1), as potential markers for breast cancer.
|
15096563 |
2004 |
|
Breast Carcinoma
|
0.090 |
Biomarker
|
disease |
BEFREE |
Although some mucins are membrane bound, our data indicate that MUCL1 is secreted by some breast cancer cells, whereas others only express high levels of intracellular MUCL1.
|
26725324 |
2016 |
|
Breast Carcinoma
|
0.090 |
Biomarker
|
disease |
BEFREE |
GCDFP15, MGB1, and SBEM were the most sensitive and specific markers to detect BC metastatic cells when at least one was expressed by quantitative RT-PCR.
|
26364839 |
2015 |
|
Breast Carcinoma
|
0.090 |
Biomarker
|
disease |
BEFREE |
SBEM has the potential to be a specific marker for predicting hematogenous micrometastasis and response to neoadjuvant chemotherapy in breast cancer.
|
20364301 |
2010 |
|
Breast Carcinoma
|
0.090 |
Biomarker
|
disease |
BEFREE |
In invasive carcinoma patients, several cellular and extracellular proteins that were significantly increased (Periostin, Small breast epithelial mucin) or decreased (Kinectin) have previously been associated with breast cancer, thereby supporting this approach for a larger disease-stage characterization effort.
|
20560667 |
2010 |
|
Breast Carcinoma
|
0.090 |
AlteredExpression
|
disease |
BEFREE |
SBEM mRNA status and time to breast cancer progression were analysed using Kaplan-Meyer curves.
|
19221791 |
2009 |
|
Breast Carcinoma
|
0.090 |
Biomarker
|
disease |
BEFREE |
SBEM tag was detected in 40 libraries (21 BC; 8 non-cancerous breast tissues).
|
18497056 |
2008 |
|
Breast Carcinoma
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Genes such as MGA, B726P and SBEM that are expressed relatively exclusively in breast tissue are potential new markers for breast cancer.
|
18253069 |
2007 |
|
Breast Carcinoma
|
0.090 |
AlteredExpression
|
disease |
BEFREE |
Clarifying the SBEM gene regulation will help to dissect mechanisms underlying transcription of normal breast and breast cancer-associated genes.
|
16720387 |
2006 |
|
Breast Carcinoma
|
0.090 |
Biomarker
|
disease |
BEFREE |
We selected three molecules, small breast epithelial mucin (SBEM), prostate epithelium-specific Ets transcription factor (PDEF), and mammaglobin (MGB1), as potential markers for breast cancer.
|
15096563 |
2004 |
|
Mammary Neoplasms
|
0.050 |
AlteredExpression
|
group |
BEFREE |
MUCL1 expression is highest in HER2-amplified breast tumors and inhibiting HER2 activity in tumor cells resulted in a decreased MUCL1 expression.
|
26725324 |
2016 |
|
Mammary Neoplasms
|
0.050 |
AlteredExpression
|
group |
LHGDN |
In silico and in vitro analysis of small breast epithelial mucin as a marker for bone marrow micrometastasis in breast cancer.
|
18497056 |
2008 |
|
Mammary Neoplasms
|
0.050 |
AlteredExpression
|
group |
BEFREE |
e human small breast epithelial mucin (SBEM) gene has been identified as being preferentially expressed in mammary epithelial cells and over-expressed in breast tumors.
|
16720387 |
2006 |
|
Mammary Neoplasms
|
0.050 |
Biomarker
|
group |
BEFREE |
Human small breast epithelial mucin: the promise of a new breast tumor biomarker.
|
15684711 |
2004 |
|
Mammary Neoplasms
|
0.050 |
Biomarker
|
group |
LHGDN |
Human small breast epithelial mucin: the promise of a new breast tumor biomarker.
|
15684711 |
2004 |
|
Mammary Neoplasms
|
0.050 |
AlteredExpression
|
group |
BEFREE |
In a subset of 20 primary breast tumors and their matched axillary lymph nodes, a high concordance (Fisher's exact test, P < 0.001) was seen between PCR detection of SBEM mRNA in lymph node tissue and their histopathological status, indicating that SBEM mRNA expression is conserved in nodal metastasis.
|
12019145 |
2002 |