Secondary malignant neoplasm of colon and/or rectum
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide association study identifies single nucleotide polymorphisms associated with time-to-metastasis in colorectal cancer.
|
30738427 |
2019 |
Alanine aminotransferase measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
|
29403010 |
2018 |
Serum Alanine Aminotransferase Measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.
|
29403010 |
2018 |
Narcolepsy
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
Genome-wide association database developed in the Japanese Integrated Database Project.
|
19629137 |
2009 |
Malignant neoplasm of stomach
|
0.010 |
Biomarker
|
disease |
BEFREE |
A miR-567-PIK3AP1-PI3K/AKT-c-Myc feedback loop regulates tumour growth and chemoresistance in gastric cancer.
|
31078520 |
2019 |
Neoplasms
|
0.010 |
Biomarker
|
group |
BEFREE |
Our studies revealed that miR-567 acts as a tumour suppressor gene and suppresses GC tumorigenesis and chemoresistance via a miR-567-PIK3AP1- PI3K/AKT-c-Myc feedback loop.
|
31078520 |
2019 |
Stomach Carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
A miR-567-PIK3AP1-PI3K/AKT-c-Myc feedback loop regulates tumour growth and chemoresistance in gastric cancer.
|
31078520 |
2019 |
Neurodevelopmental Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
We further support candidacy for neurodevelopmental disorders of four previously described genes (PIK3AP1, GTF3C3, UFC1, and WRAP53), three of which also followed a recessive inheritance pattern.
|
30552426 |
2019 |
Encephalomyelitis
|
0.010 |
Biomarker
|
disease |
BEFREE |
Consequently, mice that lack BCAP in T cells had reduced susceptibility to experimental autoimmune encephalomyelitis.
|
30093533 |
2018 |
Sarcoma
|
0.010 |
Biomarker
|
group |
BEFREE |
BCAP-1 markedly inhibited Sarcoma 180tumor growth in tumor-bearing mice, and increased the secretion of TNF-α in serum.
|
27884671 |
2017 |
Malignant neoplasm of soft tissue
|
0.010 |
Biomarker
|
group |
BEFREE |
BCAP-1 markedly inhibited Sarcoma 180tumor growth in tumor-bearing mice, and increased the secretion of TNF-α in serum.
|
27884671 |
2017 |
Burkitt Lymphoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
These corroborated the upregulation of PIK3AP1 and AKT activation in BJAB cells expressing high levels of both EBERs and EBNA1 (a surrogate of Burkitt's lymphoma EBV latency I) relative to those expressing only EBNA1.
|
26121143 |
2015 |
Adult Burkitt Lymphoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
These corroborated the upregulation of PIK3AP1 and AKT activation in BJAB cells expressing high levels of both EBERs and EBNA1 (a surrogate of Burkitt's lymphoma EBV latency I) relative to those expressing only EBNA1.
|
26121143 |
2015 |
Childhood Burkitt Lymphoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
These corroborated the upregulation of PIK3AP1 and AKT activation in BJAB cells expressing high levels of both EBERs and EBNA1 (a surrogate of Burkitt's lymphoma EBV latency I) relative to those expressing only EBNA1.
|
26121143 |
2015 |
Allergic rhinitis (disorder)
|
0.010 |
Biomarker
|
disease |
BEFREE |
Our study suggests that MRPL4 and BCAP, key components of the HIF-1α and PI3K/Akt signaling pathways respectively, are two novel candidate genes for atopy and allergic rhinitis.
|
21625490 |
2011 |