CLU, clusterin, 1191

N. diseases: 412; N. variants: 14
Disease: Malignant tumor of colon ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.080 Biomarker disease BEFREE Ectopic expression of nCLU either by epigenetic modulators or by nCLU transfection is responsible for colon cancer cell death. 25917404 2015
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.080 Biomarker disease BEFREE Clusterin, a gene enriched in intestinal stem cells, is required for L1-mediated colon cancer metastasis. 26399194 2015
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.080 Biomarker disease BEFREE Our results indicate that platelet-secreted TSP1 and clusterin promote the signal regulation of MMP-9 in platelet-induced colonic cancer invasion via a P38MAPK-regulated pathway. 24085798 2014
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.080 Biomarker disease BEFREE On the basis of results obtained by CLU immuno-dosage in blood and stool of colon cancer patients, we report that sCLU could represent a diagnostic molecular marker for colon cancer screening. 19879422 2009
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.080 Biomarker disease BEFREE Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression. 19177010 2009
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.080 Biomarker disease BEFREE Thus, clusterin is a candidate secreted colon cancer marker but not a single target for chemoprevention or therapy. 18180384 2008
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.080 Biomarker disease BEFREE A new potential stool marker of colon cancer is clusterin, a protein of particular interest for its high sensitivity and positive predictive value in patients with highly aggressive CRC. 18055195 2007
CUI: C0007102
Disease: Malignant tumor of colon
Malignant tumor of colon 		0.080 Biomarker disease BEFREE We found that transient transfection of clusterin to colon cancer cell lines directly enhanced basal and chemotherapy-induced apoptosis. 15492264 2004