SERPINA3, serpin family A member 3, 12

N. diseases: 229; N. variants: 8
Disease: Heart failure ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018801
Disease: Heart failure
Heart failure 		0.040 AlteredExpression disease BEFREE ELISA analysis confirmed a significant increase in circulating plasma Serpina3 levels in the HF group (P = .004). 31670476 2020
CUI: C0018801
Disease: Heart failure
Heart failure 		0.040 AlteredExpression disease BEFREE Circulating ACT levels were elevated in HF patients (n=18) as compared with healthy controls (n=6; P=0.001) and normalized by 6 months of LVAD support. 23640964 2013
CUI: C0018801
Disease: Heart failure
Heart failure 		0.040 Biomarker disease BEFREE Among these genes, many were observed to be involved in mitochondrial dysfunction and oxidative phosphorylation and 3 extracellular molecules, including periostin, pleiotrophin, and SERPINA3, which might become novel diagnostic and therapeutic targets for HF. 19638707 2009
CUI: C0018801
Disease: Heart failure
Heart failure 		0.040 Biomarker disease BEFREE Polymorphisms in adrenergic receptors previously demonstrated to be predictive of heart failure were not associated with ACT. 16330681 2005