TPH2, tryptophan hydroxylase 2, 121278

N. diseases: 137; N. variants: 37
Disease: Completed Suicide ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0852733
Disease: Completed Suicide
Completed Suicide 		0.060 Biomarker phenotype BEFREE None of the genetic markers within SLC6A4, MAOA, TPH1 and TPH2 were significantly associated with completed suicide or suicide method in the basic association tests. 23313272 2013
CUI: C0852733
Disease: Completed Suicide
Completed Suicide 		0.060 GeneticVariation phenotype BEFREE Association between tryptophan hydroxylase 2 gene polymorphism and completed suicide. 21198324 2010
CUI: C0852733
Disease: Completed Suicide
Completed Suicide 		0.060 Biomarker phenotype BEFREE Our finding does not support the hypothesis of TPH2 being a susceptibility factor for completed suicide in males of Estonian origin. 19356604 2009
CUI: C0852733
Disease: Completed Suicide
Completed Suicide 		0.060 GeneticVariation phenotype BEFREE This study was designed to examine whether the -473T > A and -8396G > C polymorphisms of the TPH2 gene may be associated with completed suicide in subjects with major psychoses from the Stanley Foundation Brain Bank sample. 16436194 2006
CUI: C0852733
Disease: Completed Suicide
Completed Suicide 		0.060 AlteredExpression phenotype BEFREE We hypothesized that completed suicide is associated with abnormal TPH2 expression in the brain. 15941494 2006
CUI: C0852733
Disease: Completed Suicide
Completed Suicide 		0.060 GeneticVariation phenotype BEFREE This is the first report about an association between TPH2 gene polymorphisms and completed suicide. 15476687 2004