TDRD9, tudor domain containing 9, 122402

N. diseases: 26; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C4021107
Disease: Non-obstructive azoospermia
Non-obstructive azoospermia
0.110 GeneticVariation disease BEFREE Mutation in TDRD9 causes non-obstructive azoospermia in infertile men. 28536242 2017
CUI: C0004509
Disease: Azoospermia
Azoospermia
0.110 AlteredExpression disease BEFREE Impaired expression of the DDX4, MAEL,MOV10L1, PIWIL2, PIWIL4, and TDRD9 genes in the group of cryptorchid boys at high risk of infertility indicates that gene instability induced by impaired expression of transposon silencing genes contribute to the development of azoospermia. 22223142 2011
CUI: C0004509
Disease: Azoospermia
Azoospermia
0.110 Biomarker disease HPO
CUI: C4021107
Disease: Non-obstructive azoospermia
Non-obstructive azoospermia
0.110 Biomarker disease HPO
CUI: C0241355
Disease: Small testicle
Small testicle
0.100 Biomarker phenotype HPO
Increased circulating gonadotropin level
0.100 Biomarker phenotype HPO
CUI: C3279550
Disease: Cryptozoospermia
Cryptozoospermia
0.100 Biomarker phenotype HPO
CUI: C4023106
Disease: Obstructive azoospermia
Obstructive azoospermia
0.100 Biomarker disease HPO
CUI: C0006142
Disease: Malignant neoplasm of breast
Malignant neoplasm of breast
0.010 GeneticVariation disease BEFREE We examined the psychometric properties, particularly the factorial validity, of the HLS-EU-Q in women with breast cancer. 28221213 2019
CUI: C0006826
Disease: Malignant Neoplasms
Malignant Neoplasms
0.010 Biomarker group BEFREE There were 33 items included in the C-HLS for validation; 360 newly diagnosed cancer patients completed the survey. 30998604 2019
CUI: C0007789
Disease: Cerebral Palsy
Cerebral Palsy
0.010 Biomarker disease BEFREE This retrospective cohort study included 87 ambulatory children with CP who underwent HLS surgery with both preoperative and postoperative gait analysis (mean time, 29.4±19.9 mo after surgery) testing between 1997 and 2015. 31305380 2019
CUI: C0020538
Disease: Hypertensive disease
Hypertensive disease
0.010 Biomarker group BEFREE Among the components of the score, BMI was apparently the main factor driving the association between the HLS and lower risk of hypertension. 30902699 2019
CUI: C0035328
Disease: Retinal Vein Occlusion
Retinal Vein Occlusion
0.010 GeneticVariation disease BEFREE This cross-sectional questionnaire study used the validated HLS-EU-Q16 questionnaire to determine the health literacy of 225 patients with age-related macular degeneration (AMD), diabetic macular edema (DME) or retinal vein occlusion (RVO), receiving intravitreal treatment at the retinal clinic, Zealand University Hospital, Denmark. 31395040 2019
CUI: C0242383
Disease: Age related macular degeneration
Age related macular degeneration
0.010 Biomarker disease BEFREE This cross-sectional questionnaire study used the validated HLS-EU-Q16 questionnaire to determine the health literacy of 225 patients with age-related macular degeneration (AMD), diabetic macular edema (DME) or retinal vein occlusion (RVO), receiving intravitreal treatment at the retinal clinic, Zealand University Hospital, Denmark. 31395040 2019
CUI: C0678222
Disease: Breast Carcinoma
Breast Carcinoma
0.010 GeneticVariation disease BEFREE We examined the psychometric properties, particularly the factorial validity, of the HLS-EU-Q in women with breast cancer. 28221213 2019
CUI: C0730285
Disease: Diabetic macular edema
Diabetic macular edema
0.010 GeneticVariation disease BEFREE This cross-sectional questionnaire study used the validated HLS-EU-Q16 questionnaire to determine the health literacy of 225 patients with age-related macular degeneration (AMD), diabetic macular edema (DME) or retinal vein occlusion (RVO), receiving intravitreal treatment at the retinal clinic, Zealand University Hospital, Denmark. 31395040 2019
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.010 Biomarker group BEFREE There were 33 items included in the C-HLS for validation; 360 newly diagnosed cancer patients completed the survey. 30998604 2019
CUI: C0002395
Disease: Alzheimer's Disease
Alzheimer's Disease
0.010 Biomarker disease BEFREE Intranasal delivery of HLS-3 with better pharmacokinetics and pharmacodynamics performances provides a promising approach for treatment of Alzheimer's disease. 29966606 2018
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis
0.010 GeneticVariation disease BEFREE Among the 3 components of the HLS , abstinence from smoking had the strongest association with subclinical atherosclerosis. 30482079 2018
CUI: C0004153
Disease: Atherosclerosis
Atherosclerosis
0.010 GeneticVariation disease BEFREE Among the 3 components of the HLS , abstinence from smoking had the strongest association with subclinical atherosclerosis. 30482079 2018
CUI: C0007097
Disease: Carcinoma
Carcinoma
0.010 Biomarker group BEFREE Thus, our results place TDRD9 as a marker for prognosis and as a potential therapeutic target in a subset of lung carcinomas. 29515758 2018
CUI: C0152013
Disease: Adenocarcinoma of lung (disorder)
Adenocarcinoma of lung (disorder)
0.010 AlteredExpression disease BEFREE Furthermore, <i>TDRD9</i> expression is associated with poor prognosis in lung adenocarcinoma. 29515758 2018
CUI: C0155017
Disease: Color Blindness, Blue
Color Blindness, Blue
0.010 Biomarker disease BEFREE Compared with the HLS + CBT control condition, the ERT + CBT condition demonstrated higher abstinence rates at 2 months (ERT + CBT = 23% vs. HLS + CBT = 0%, OR = 13.51; 95% CI = 0.70-261.59) and 4 months (ERT = 18% vs. HLS = 5%; OR = 2.98; 95% CI = 0.39-22.72) post-quit. 28403472 2017
CUI: C1847540
Disease: Azoospermia, Nonobstructive
Azoospermia, Nonobstructive
0.010 Biomarker disease BEFREE To this end, five single-nucleotide polymorphisms (SNPs) in the ASZ1, PIWIL1, TDRD1, and TDRD9 genes were genotyped by TaqMan allelic discrimination assays in 342 cases of nonobstructive azoospermia (NOA) and 493 controls. 27233649 2016
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.010 Biomarker group BEFREE Although microsurgery has considerably improved post-operative results, multifocal tumour development and recurrence remain a serious problem in the clinical management of HLS gene carriers. 1431953 1992