PLIN2, perilipin 2, 123

N. diseases: 100; N. variants: 3
Disease: Dyslipidemias ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias 		0.020 Biomarker group BEFREE <i>In vivo</i> ceramide reduction by inhibition of <i>de novo</i> ceramide synthesis reduced PLIN2 and hepatic steatosis in alcohol-fed mice, but only <i>de novo</i> synthesis inhibition, not sphingomyelin hydrolysis, improved glucose tolerance and dyslipidemia. 28864659 2018
CUI: C0242339
Disease: Dyslipidemias
Dyslipidemias 		0.020 GeneticVariation group BEFREE The aim of this study was to evaluate the effect of the Ser251Pro mutation of PLIN2 gene in a cohort with a higher predisposition to obesity-associated metabolic alterations, such as insulin resistance, decreased insulin-secretion, hyperglycaemia, and dyslipidaemia. 26443937 2016