CCR5, C-C motif chemokine receptor 5 (gene/pseudogene), 1234
N. diseases: 508; N. variants: 15
Source: ALL
| Disease | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year |
|---|---|---|---|---|---|---|---|
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0.040 | Biomarker | disease | BEFREE | We have previously shown the existence of primary human immunodeficiency virus type 2 isolates (MIC97 and MJC97) unable to use major coreceptors to entry into peripheral blood mononuclear cells, including CCR5 and CXCR4. | 19200444 | 2009 |
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0.040 | Biomarker | disease | BEFREE | Increased frequency of circulating CCR5+ CD4+ T cells in human immunodeficiency virus type 2 infection. | 17035326 | 2006 |
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0.040 | GeneticVariation | disease | BEFREE | Using GHOST indicator cells, we showed for the first time that the only coreceptors efficiently used by low-pathogenic HIV-2 variants are CCR5, GPR15 (BOB), and CXCR6 (BONZO). | 15650194 | 2005 |
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|
0.040 | Biomarker | disease | BEFREE | Small amino acid changes in the V3 loop of human immunodeficiency virus type 2 determines the coreceptor usage for CXCR4 and CCR5. | 10544150 | 1999 |