CCR7, C-C motif chemokine receptor 7, 1236

N. diseases: 320; N. variants: 3
Disease: Arteriosclerosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 Biomarker disease BEFREE The present study investigated the potential association between mTOR signaling and SIRT1‑LXR‑CCR7/NF‑κB signaling (SIRT1 signaling) in AS pathogenesis. 28765952 2017
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 Biomarker disease BEFREE These data suggest that the CCL19/CCL21-CCR7 axis plays an important role in atherosclerosis progression. 24990231 2014
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 AlteredExpression disease BEFREE Statins promote the regression of atherosclerosis via activation of the CCR7-dependent emigration pathway in macrophages. 22163030 2011
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 AlteredExpression disease BEFREE We conclude that LXR is required for maximal effects on plaque CD68+ cell expression of CCR7 and monocyte-derived cell egress during atherosclerosis regression in mice. 21041949 2010
CUI: C0003850
Disease: Arteriosclerosis
Arteriosclerosis 		0.050 Biomarker disease BEFREE Gene expression changes in foam cells and the role of chemokine receptor CCR7 during atherosclerosis regression in ApoE-deficient mice. 16537455 2006