CCR7, C-C motif chemokine receptor 7, 1236

N. diseases: 320; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0018133
Disease: Graft-vs-Host Disease
Graft-vs-Host Disease
0.030 Biomarker disease BEFREE Multivariate analysis revealed that both HLA mismatching and CCR7 downregulation on donors' CD4+ T cells after mobilization were independent risk factors for acute graft-versus-host disease (GVHD). 28965881 2018
CUI: C0018133
Disease: Graft-vs-Host Disease
Graft-vs-Host Disease
0.030 Biomarker disease BEFREE CCR7 and CXCR3 are two receptors associated with the development of GVHD. 23179902 2012
CUI: C0018133
Disease: Graft-vs-Host Disease
Graft-vs-Host Disease
0.030 Biomarker disease BEFREE CCR7(-/-) regulatory T cells were able to protect against lethal GVHD when administered before WT conventional T cells. 20185583 2010