LTB4R, leukotriene B4 receptor, 1241

N. diseases: 107; N. variants: 0
Disease: Pneumonitis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C3714636
Disease: Pneumonitis
Pneumonitis 		0.030 Biomarker disease BEFREE Consequently, bone marrow chimeric mice lacking BLT1 in radio-resistant structural cells failed to develop allergic lung inflammation to papain. 30390302 2019
CUI: C3714636
Disease: Pneumonitis
Pneumonitis 		0.030 Biomarker disease BEFREE Interestingly, BLT1 blockade after the occurrence of lung metastases had no effect on the magnitude of lung metastasis, suggesting that inhibition of BLT1-mediated lung inflammation was insufficient to suppress established metastatic tumor. 29884308 2018
CUI: C3714636
Disease: Pneumonitis
Pneumonitis 		0.030 Biomarker disease BEFREE Here, we developed a novel murine model of acute lung rejection to demonstrate that BLT1 controls effector CD8+ T cell trafficking into the lung and that disruption of BLT1 signaling in CD8+ T cells reduces lung inflammation and mortality in the model. 15998790 2005