CNR1, cannabinoid receptor 1, 1268

N. diseases: 393; N. variants: 21
Disease: Cocaine Abuse ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker disease BEFREE Our findings add to the evidence that drugs targeting CB1 receptors are good candidates for the treatment of cocaine abuse and provide further insights into the mechanisms underlying endocannabinoid signaling within the brain reward system in the context of cocaine abuse. 28366798 2017
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker disease CTD_human Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample. 19052543 2009
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker disease CTD_human Role of cannabinoid type 1 receptors in locomotor activity and striatal signaling in response to psychostimulants. 17596442 2007
CUI: C0009171
Disease: Cocaine Abuse
Cocaine Abuse 		0.310 Biomarker disease CTD_human (AAT)n repeat in the cannabinoid receptor gene (CNR1): association with cocaine addiction in an African-Caribbean population. 16314880 2006