CNR1, cannabinoid receptor 1, 1268

N. diseases: 393; N. variants: 21
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.340 GeneticVariation disease BEFREE A cannabinoid receptor 1 polymorphism is protective against major depressive disorder in methadone-maintained outpatients. 26331953 2015
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.340 Biomarker disease PSYGENET The role of CNR1 gene (rs806368, rs1049353, rs806371, rs806377 and rs1535255) was investigated in 319 outpatients with MD and 150 healthy individuals. 23407780 2013
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.340 GeneticVariation disease BEFREE The role of CNR1 gene (rs806368, rs1049353, rs806371, rs806377 and rs1535255) was investigated in 319 outpatients with MD and 150 healthy individuals. 23407780 2013
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.340 Biomarker disease PSYGENET The CB1 levels in the PFC of major depression patients were higher when compared to the age-matched controls (adj. p < 0.05). 22534181 2012
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.340 GeneticVariation disease BEFREE We assessed the CB1 receptor gene (CNR1) single nucleotide polymorphism (SNP) rs1049353 (rs1049353" genes_norm="1268">1359 G/A) and the fatty acid amide hydrolase (FAAH) gene rs324420 SNP (cDNA 385C to A) for their associations with MD and/or BD in 83 Caucasian patients with recurrent MD, 134 Caucasian individuals with BD, and 117 Caucasian healthy subjects. 20080186 2010
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.340 Biomarker disease PSYGENET We assessed the CB1 receptor gene (CNR1) single nucleotide polymorphism (SNP) rs1049353 (1359 G/A) and the fatty acid amide hydrolase (FAAH) gene rs324420 SNP (cDNA 385C to A) for their associations with MD and/or BD in 83 Caucasian patients with recurrent MD, 134 Caucasian individuals with BD, and 117 Caucasian healthy subjects. 20080186 2010
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.340 GeneticVariation disease BEFREE Therefore, the impact of cannabinoid receptor 1 gene (CNR1) variants rs1049353 and rs12720071 on antidepressant treatment response was evaluated in 256 Caucasian patients with Major Depression. 18579347 2008
CUI: C0041696
Disease: Unipolar Depression
Unipolar Depression
0.340 Biomarker disease PSYGENET Therefore, the impact of cannabinoid receptor 1 gene (CNR1) variants rs1049353 and rs12720071 on antidepressant treatment response was evaluated in 256 Caucasian patients with Major Depression. 18579347 2008