CNTF, ciliary neurotrophic factor, 1270

N. diseases: 114; N. variants: 3
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1998028
Disease: Photoreceptor degeneration
Photoreceptor degeneration
0.040 Biomarker disease BEFREE The intraocular administration of the ciliary neurotrophic factor (CNTF) has been found to attenuate the photoreceptor degeneration and preserve retinal functions in the animal research models of the inherited or induced retinal disease. 29065723 2018
CUI: C1998028
Disease: Photoreceptor degeneration
Photoreceptor degeneration
0.040 Biomarker disease BEFREE Employing a murine model of retinal disease, we demonstrate that ciliary neurotrophic factor (CNTF) confers life-long protection against photoreceptor degeneration. 25896245 2015
CUI: C1998028
Disease: Photoreceptor degeneration
Photoreceptor degeneration
0.040 Biomarker disease BEFREE It was found that CNTF had a potent effect on delaying the photoreceptor degeneration process in RCS rats. 14730208 2004
CUI: C1998028
Disease: Photoreceptor degeneration
Photoreceptor degeneration
0.040 Biomarker disease BEFREE Anti-apoptotic effects of CNTF gene transfer on photoreceptor degeneration in experimental antibody-induced retinopathy. 12935781 2003