COL1A1, collagen type I alpha 1 chain, 1277

N. diseases: 487; N. variants: 337
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 Biomarker disease BEFREE Inhibition of COL1A1 in KRASWT and KRASMUT CRC cell lines significantly decreased cell proliferation and invasion. 30132520 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 Biomarker disease BEFREE The results of correlation study showed that the expression of HK3 demonstrated a strong correlation with 7 of the 21 examined genes (ZEB2, GREM1, TGFB3, TGFB1, SNAI2, TWIST1, and COL1A1) in CRC. 29504907 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma
0.030 Biomarker disease BEFREE In summary, the present data indicated that COL1A1 may serve as an oncoprotein, and that it may be used as a potential therapeutic target in CRC. 29393423 2018