COL1A1, collagen type I alpha 1 chain, 1277

N. diseases: 487; N. variants: 337
Disease: Fibroid Tumor ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023267
Disease: Fibroid Tumor
Fibroid Tumor 		0.030 Biomarker disease BEFREE Main outcome measures were MiR-21-5p overexpression, target gene and protein expression, collagen (COL1A1) production, cell proliferation, cell migration, and cell cycle stages of fibroid and myometrial immortalized cell lines. 29747655 2018
CUI: C0023267
Disease: Fibroid Tumor
Fibroid Tumor 		0.030 AlteredExpression disease BEFREE Leiomyoma cells treated with cetrorelix for 6 hours showed a decreased expression of GnRHR1 (0.5 ± 0.15-fold), COL1A1 (3.79 ± 0.7-fold), fibronectin (0.92 ± 0.09-fold), and versican variant V0 (0.14 ± 0.07-fold). 22901846 2012
CUI: C0023267
Disease: Fibroid Tumor
Fibroid Tumor 		0.030 AlteredExpression disease LHGDN Thrombospondin-1 was consistently underexpressed in both the edge and center of the fibroids, while COL1A1 and COL3A1 were consistently overexpressed. 18089612 2007