|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Immunofluoresence assay indicates NOR1 protein is mainly expressed at CD163 positive M2 tumor associated macrophages (TAMs).
|
29227538 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
We also found that NOR1 expression decreased cancer stem-like cell properties of NPC cells, reduced their ability to form tumor spheroids in vitro, reduced tumorigenicity in nude mice in vivo, and increased sensitivity to chemotherapy agents.
|
27891591 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Previous studies have reported that the oxidored-nitro domain containing protein 1 (NOR1) is a novel tumor suppressor in several tumors.
|
28232113 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Deciphering the molecular mechanisms underlying NOR1 mediated tumor suppressive role would be helpful to a deeper understanding of carcinogenesis and, furthermore, to the development of new therapeutic approaches.
|
28367242 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Oxidored-nitro domain containing protein 1 (NOR1) is a putative tumor suppressor gene.
|
24657653 |
2014 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Previous studies have reported that oxidored-nitro domain containing protein 1 (NOR1) is a novel tumor suppressor gene identified in various types of cancer, such as nasopharyngeal carcinoma and cervical cancer.
|
25118646 |
2014 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
NOR1 is a putative tumor suppressor gene.
|
23831407 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Therefore, NOR1 is an important tumor suppressor gene associated with NPC and CCA and may play antitumor roles by inhibiting proliferation, preventing colony formation, and promoting the apoptosis of tumor cells via the mitochondrial-dependent apoptotic pathway.
|
23124592 |
2013 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Frequent epigenetic inactivation of the NOR1 gene in NPC suggests that it may be a critical tumor suppressor involved in the development of NPC.
|
21803736 |
2011 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
The EWS/NOR-1 fusion protein is encoded by the t(9;22) chromosomal translocation found in approximately 75% of extraskeletal myxoid chondrosarcoma (EMC) tumors.
|
15212958 |
2004 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
NOR-1 is normally involved in the balance between cell proliferation and cell death, and is implicated in oncogenesis as part of the EWS/NOR-1 fusion protein found in human extraskeletal myxoid chondrosarcoma (EMC) tumors.
|
12543801 |
2003 |
|
Neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
We cloned a novel gene NOR(1), and the Glu58Gly polymorphism of NOR(1) may be involved in the development and/or progression of NPC suggesting that NOR(1) could be a candidate tumor repressor gene related with NPC.
|
12819961 |
2003 |