COMT, catechol-O-methyltransferase, 1312

N. diseases: 622; N. variants: 47
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0004930
Disease: Behavior Disorders
Behavior Disorders
0.310 Biomarker group CTD_human [The relationship between gene polymorphism of catechol-O-methyltransferase and survival of oral pesticides suicide attempters]. 16780746 2006
CUI: C0004930
Disease: Behavior Disorders
Behavior Disorders
0.310 GeneticVariation group BEFREE Of special interest is the role of this gene in major psychoses especially since a microdeletion (22q11) containing the COMT gene (velo-cardio-facial syndrome) also carries with it several types of behavioral disorders, including an increased prevalence of schizophrenia. 12707935 2003