COMT, catechol-O-methyltransferase, 1312

N. diseases: 622; N. variants: 47
Disease: Acute postoperative pain ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2215257
Disease: Acute postoperative pain
Acute postoperative pain 		0.030 Biomarker phenotype BEFREE Genetic variability at COMT but not at OPRM1 and UGT2B7 loci modulates morphine analgesic response in acute postoperative pain. 23686330 2013
CUI: C2215257
Disease: Acute postoperative pain
Acute postoperative pain 		0.030 GeneticVariation phenotype BEFREE Effect of catechol-o-methyltransferase-gene (COMT) variants on experimental and acute postoperative pain in 1,000 women undergoing surgery for breast cancer. 24343288 2013
CUI: C2215257
Disease: Acute postoperative pain
Acute postoperative pain 		0.030 GeneticVariation phenotype BEFREE The results indicate that genetic variations in COMT contribute to the acute postoperative pain and analgesia responses and physiologic responses in this group of otherwise healthy postoperative orthopedic trauma patients. 22718527 2013