KLF6, Kruppel like factor 6, 1316

N. diseases: 204; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0017638
Disease: Glioma
Glioma
0.350 Biomarker disease BEFREE Additionally, procaspase-3 expressing glioma and meningioma cell lines were sensitive to the apoptotic effects of PAC-1 at biologically relevant exposures achievable in cancer patients. 30859090 2019
CUI: C0017638
Disease: Glioma
Glioma
0.350 Biomarker disease BEFREE Furthermore, the interaction between LINC00052 and kruppel-like factor 6 (KLF6) in mediating the progression of glioma was studied by performing qRT-PCR and Western blot. 31210314 2019
CUI: C0017638
Disease: Glioma
Glioma
0.350 Biomarker disease BEFREE We investigated PAC-1 as a single agent and in combination with TMZ against glioma cells in culture and in orthotopic rodent models of glioma. 29113289 2017
CUI: C0017638
Disease: Glioma
Glioma
0.350 Biomarker disease BEFREE Our study demonstrates that quantification of total and spliced forms of KLF6 may provide a new and useful supplementary molecular tool for grading glioma. 20545576 2010
CUI: C0017638
Disease: Glioma
Glioma
0.350 AlteredExpression disease BEFREE Relative to normal human brain, PAC1-R expression is significantly upregulated in glioma, particularly oligodendrogliomas. 10867818 2000
CUI: C0017638
Disease: Glioma
Glioma
0.350 CausalMutation disease CGI