KLF6, Kruppel like factor 6, 1316

N. diseases: 204; N. variants: 9
Disease: Schizophrenia ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.040 Biomarker disease BEFREE The neuroprotective effect via PAC-1 activation suggests a potentially novel pharmacological target for the treatment of schizophrenia, via neurogenesis normalization. 28125634 2017
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.040 Biomarker disease BEFREE Mice lacking the gene encoding pituitary adenylate cyclase-activating polypeptide (PACAP) or its specific receptor, PAC1, show abnormal behaviors related to schizophrenia. 27383213 2016
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.040 GeneticVariation disease BEFREE In addition, an association between SNPs of the PACAP or PAC1 genes and schizophrenia has been reported. 19958095 2009
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.040 GeneticVariation disease BEFREE Here, we provide evidence that genetic variants of the genes encoding PACAP and its receptor, PAC1, are associated with schizophrenia. 17387318 2007