KLF6, Kruppel like factor 6, 1316

N. diseases: 204; N. variants: 9
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis
0.030 Biomarker disease BEFREE The Krüppel like factor 6 (KLF6) gene encodes multiple protein isoforms derived from alternative mRNA splicing, most of which are intimately involved in hepatocarcinogenesis and tumor progression. 24921656 2014
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis
0.030 Biomarker disease BEFREE The aim of the study was to evaluate the impact of KLF6 depletion on human HCC and experimental hepatocarcinogenesis in vivo. 21563203 2011
CUI: C1512409
Disease: Hepatocarcinogenesis
Hepatocarcinogenesis
0.030 AlteredExpression disease BEFREE Downregulation of KLF6 is an early event in hepatocarcinogenesis, and stimulates proliferation while reducing differentiation. 17196295 2007