Disease: LEBER CONGENITAL AMAUROSIS 12 (disorder) ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1857743
Disease: LEBER CONGENITAL AMAUROSIS 12 (disorder)
LEBER CONGENITAL AMAUROSIS 12 (disorder) 		0.010 GeneticVariation disease BEFREE To further investigate the role of RD3 in photoreceptors and explore gene therapy as a potential treatment for LCA12, we delivered adeno-associated viral vector (AAV8) with a Y733F capsid mutation and containing the mouse Rd3 complementary DNA (cDNA) under the control of the human rhodopsin kinase promoter to photoreceptors of 14-day-old Rb(11.13)4Bnr/J and In (5)30Rk/J strains of rd3 mice by subretinal injections. 23740938 2013