|
Atrial Fibrillation
|
0.010 |
Biomarker
|
disease |
BEFREE |
Co-immunoprecipitation and GST pull-down assays demonstrate that lamin A/C interacts with NUP155, which is a nucleoporin and causes AF when mutated.
|
30488537 |
2019 |
|
Cerebral Palsy
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
On the other hand, tissue antioxidant levels (GSH, GST, and catalase) showed a significant increase in LA-Q-ORMOSIL treated group compared to the CP treated group confirming its high therapeutic efficacy during liver injury.
|
31819411 |
2019 |
|
Colonic Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
Expression of CYP and GST in human normal and colon tumor tissues.
|
30092668 |
2019 |
|
Scleroderma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
GST is also over-expressed in autoimmune disease like scleroderma, and in kidney transplant patients and it may be used to check the efficiency of transplanted kidneys.
|
31357662 |
2019 |
|
Sensorineural Hearing Loss (disorder)
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Our results suggest that no significant relationship was found between GST M1 and T1 polymorphisms and the susceptibility to acquired SNHL.
|
30696891 |
2019 |
|
Heart failure
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We aimed to determine whether GST genotypes exhibit differential risk effects between coronary artery disease (CAD) and idiopathic dilated cardiomyopathy (IDC) in HF patients.
|
31275451 |
2019 |
|
Keratosis Follicularis
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Rhythmic expressions of metabolic detoxification genes, GSTs1 and CYP397A1 displayed similar expression patterns with total GST and P450 enzyme activities in LD and DD conditions, respectively.
|
31206537 |
2019 |
|
Lichen disease
|
0.010 |
Biomarker
|
disease |
BEFREE |
The objective of this study was to examine inhibitory effects of Usnic Acid (UA), a well-known lichen secondary metabolite, and Carnosic Acid (CA), the primary antioxidant compound of Rosmarinus officinalis L., on purified Human Paraoxonase, (PON1), Glutathione Reductase (GR) and Glutathione S-Transferase (GST).
|
30827223 |
2019 |
|
Liver diseases
|
0.010 |
Biomarker
|
group |
BEFREE |
We aimed to investigate the significance of <i>α</i>-GST evaluation in monitoring of liver injury in acute and chronic liver diseases.
|
31772928 |
2019 |
|
Myopathy
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Glutathione S-transferase (GST) pull-down experiments found novel binding partners with the SRR, several of which are associated with myopathies.
|
30689900 |
2019 |
|
Myocardial Infarction
|
0.010 |
Biomarker
|
disease |
BEFREE |
The TIMP peptide enclosed between GST and bFGF responds to MMPs for on-demand release during MI.
|
31408234 |
2019 |
|
Peripheral Neuropathy
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Furthermore, <i>GST Pi 1</i> (<i>GSTP1</i>) polymorphism is associated with peripheral neuropathy.
|
30854066 |
2019 |
|
Diastrophic dysplasia
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Rhythmic expressions of metabolic detoxification genes, GSTs1 and CYP397A1 displayed similar expression patterns with total GST and P450 enzyme activities in LD and DD conditions, respectively.
|
31206537 |
2019 |
|
Memory impairment
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
This resulted in the reduction of GSH and GST, an increase in mitochondrial DNA damage and memory impairment.
|
31376681 |
2019 |
|
Parkinsonian Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
The study aimed to explore the role of GST-π in Zn-induced Parkinsonism and its underlying molecular mechanism.
|
30076580 |
2019 |
|
Childhood Medulloblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to explore the contributions of single nucleotide polymorphisms (SNPs) in two genes, peroxisome proliferator activated receptor (PPAR) and glutathione-S-transferase (GST), to changes in general intellectual functioning in medulloblastoma survivors.
|
30607709 |
2019 |
|
Adult Medulloblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
The aim of this study was to explore the contributions of single nucleotide polymorphisms (SNPs) in two genes, peroxisome proliferator activated receptor (PPAR) and glutathione-S-transferase (GST), to changes in general intellectual functioning in medulloblastoma survivors.
|
30607709 |
2019 |
|
Poisoning syndrome
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
In the initial stages of toxicosis and/or fungal infection (12 h posttreatment), increases in the activity of insect detoxifying enzymes (GST and EST) and acid proteases are observed after monotreatments, and these increases are suppressed after combined treatment with the fungus and avermectins.
|
31667017 |
2019 |
|
Forgetful
|
0.010 |
Biomarker
|
phenotype |
BEFREE |
This resulted in the reduction of GSH and GST, an increase in mitochondrial DNA damage and memory impairment.
|
31376681 |
2019 |
|
Cardiomyopathies
|
0.010 |
Biomarker
|
group |
BEFREE |
The variants of Apolipoprotein E (ApoE) and Glutathione S-transferase (GST) may play a role in oxidative damage-induced cardiomyopathy, so we aimed to study the association of genetic variants of these genes on diastolic dysfunction in our patients.
|
30095041 |
2019 |
|
precancerous lesions
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
And, the irrigative wastewater significantly increased GST-p in the liver of rats at both the transcriptional and translational levels dose-dependently, eventually causing precancerous lesions in the liver tissues.
|
31549677 |
2019 |
|
Glucocorticoid-remediable aldosteronism
|
0.010 |
Biomarker
|
disease |
BEFREE |
Specific binding between GST and GSH significantly improves the amount of GST-TIMP-bFGF loaded in collagen-GSH hydrogel.
|
31408234 |
2019 |
|
Cardiomyopathy, Familial Idiopathic
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
We aimed to determine whether GST genotypes exhibit differential risk effects between coronary artery disease (CAD) and idiopathic dilated cardiomyopathy (IDC) in HF patients.
|
31275451 |
2019 |
|
Cleft palate, isolated
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
On the other hand, tissue antioxidant levels (GSH, GST, and catalase) showed a significant increase in LA-Q-ORMOSIL treated group compared to the CP treated group confirming its high therapeutic efficacy during liver injury.
|
31819411 |
2019 |
|
Triple Negative Breast Neoplasms
|
0.010 |
Biomarker
|
disease |
BEFREE |
By developing an enzyme-substrate trapping strategy coupled with TAP-TAG or orthogonal GST- purification followed by mass spectrometry, we identify adenylosuccinate lyase (ADSL) as an EglN2 hydroxylase substrate in triple negative breast cancer (TNBC).
|
31729379 |
2019 |