ADORA2A, adenosine A2a receptor, 135

N. diseases: 213; N. variants: 10
Disease: Memory impairment ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0233794
Disease: Memory impairment
Memory impairment 		0.020 Biomarker phenotype BEFREE Exacerbation of C1q dysregulation, synaptic loss and memory deficits in tau pathology linked to neuronal adenosine A2A receptor. 31599329 2019
CUI: C0233794
Disease: Memory impairment
Memory impairment 		0.020 PosttranslationalModification phenotype BEFREE Optogenetic activation of intracellular adenosine A2A receptor signaling in the hippocampus is sufficient to trigger CREB phosphorylation and impair memory. 25687775 2015