Breast Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Ki-67 assessment in early breast cancer: SAKK28/12 validation study on the IBCSG VIII and IBCSG IX cohort.
|
31537812 |
2019 |
Breast Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
COX regression analysis showed that FEAT was an independent prognostic factor for recurrence in breast cancer, but not for survival.
|
27881013 |
2019 |
Breast Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
The risk factors for the prognosis of patients with different subtypes of BC were analyzed using Kaplan‑Meier and COX regression analyses.
|
29620140 |
2018 |
Breast Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Previously, we have found that the number of COX-2<sup>+</sup> TAMs was associated with lymph node metastasis in breast cancer.
|
27994517 |
2016 |
Breast Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
We hypothesized that genes in ALOX/COX pathways and CRP polymorphisms would be associated with breast cancer risk and mortality in our sample of Hispanic/Native American (NA) (1430 cases, 1599 controls) and non-Hispanic white (NHW) (2093 cases, 2610 controls) women.
|
25339205 |
2015 |
Breast Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
We evaluated the effect of etodolac, an FDA-approved NSAID reported to inhibit cyclooxygenase (COX) enzymes and the retinoid X receptor alpha (RXR), on rationally identified potential biomarkers in breast cancer.
|
26275572 |
2015 |
Breast Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Multivariate Cox regression and stepwise COX regression analyses suggested that rs3787268 may be a candidate independent biomarker to predict breast cancer survival in this population.
|
23570558 |
2013 |
Breast Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Moreover, the CacyBP expression was significantly negatively associated with the COX expression in the 132 breast cancer samples (correlation coefficient = 0.505, P<0.001).
|
20878073 |
2010 |
Breast Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Here, we report that 15-deoxy-Delta(12,14)-prostaglandin J(2) (15d-PGJ(2)), one of the final products of COX-mediated arachidonic acid metabolism, upregulates the expression of COX-2 in the human breast cancer MCF-7 cell line.
|
18192694 |
2008 |
Breast Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Aromatase levels in breast cancer cells are enhanced by prostaglandins and reduced by COX inhibitors.
|
16480277 |
2006 |
Breast Carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Higher levels of COX-2 isoform were observed in breast cancer tissue when compared to normal breast tissue, and a strong association between CYP19 gene expression and the expression of COX genes are found.
|
16498361 |
2006 |
Breast Carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Frozen sections from breast cancer primary tumours (tumour n = 114, background n = 30) were immunostained with VE-cadherin, factor VIII and PECAM-1 antibodies and microvessel number was assessed.
|
15810954 |
2005 |
Breast Carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
These results are applied to published data from the BRCA1 locus (associated with early onset breast cancer) and the factor VIII locus (associated with hemophilia A) in humans.
|
9409841 |
1997 |