CPB2, carboxypeptidase B2, 1361

N. diseases: 148; N. variants: 11
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.060 Biomarker group BEFREE Procarboxypeptidase U (proCPU, TAFI, proCPB2) in cerebrospinal fluid during ischemic stroke is associated with stroke progression, outcome and blood-brain barrier dysfunction. 29194929 2018
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.060 AlteredExpression group BEFREE The dose-response curve showed that, as a whole, with the increase of TAFI levels, the relative risk of stroke first increased and then decreased (p=0.0127). 28890533 2017
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.060 GeneticVariation group BEFREE Thrombin activatable fibrinolysis inhibitor gene polymorphisms are associated with antigenic levels in the Asian-Indian population but may not be a risk for stroke. 18986391 2008
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.060 Biomarker group BEFREE AP showed associations with all 4 major subtypes of ischemic stroke and intact TAFI to large vessel disease and cryptogenic stroke. 17272741 2007
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.060 AlteredExpression group LHGDN AP showed associations with all 4 major subtypes of ischemic stroke and intact TAFI to large vessel disease and cryptogenic stroke. 17272741 2007
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.060 AlteredExpression group LHGDN Thrombin activatable fibrinolysis inhibitor and its relationship to fibrinolysis and inflammation during the acute and convalescent phase of ischemic stroke. 17473579 2007
CUI: C0038454
Disease: Cerebrovascular accident
Cerebrovascular accident
0.060 AlteredExpression group BEFREE This indicates that increased functional TAFI levels after stroke are not caused by an acute phase reaction. 16092924 2005