CPE, carboxypeptidase E, 1363

N. diseases: 101; N. variants: 7
Disease: Depressive disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.020 Biomarker disease BEFREE Mutations in the CPE gene, which encodes carboxypeptidase E (CPE), have been linked to depression and intellectual disability. 29982499 2019
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.020 GeneticVariation disease BEFREE A human carboxypeptidase E/NF-α1 gene mutation in an Alzheimer's disease patient leads to dementia and depression in mice. 27922637 2016