VPS37A, VPS37A subunit of ESCRT-I, 137492

N. diseases: 55; N. variants: 2
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE Therefore, HCRP1 may function as a tumor suppressor in ESCC progression. 31152734 2019
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 AlteredExpression group BEFREE The negative expression of HCRP-1 was significantly correlated with tumor size (P = 0.033), PT status (P = 0.001), TNM stage (P = 0.039), and histological grade (P = 0.01). 30518879 2018
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE Previous studies showed that HCRP1 is decreased in tumor cells compared with normal tissue, and functions as a tumor suppressor. 28458158 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 AlteredExpression group BEFREE HCRP1 expression was significantly related to age (P=0.017), pathological grade (P=0.003), tumor encapsulation (P=0.037), recurrence (P=0.039) and death (P=0.015), but unrelated to cirrhosis (P=0.216), tumor size (P=0.273), and distant metastasis (P=0.554). 28122307 2017
CUI: C0027651
Disease: Neoplasms
Neoplasms
0.050 Biomarker group BEFREE We propose that hVps37A status could become a novel prognostic and therapeutic marker for EGFR or HER2 driven tumors. 22016507 2011