CR2, complement C3d receptor 2, 1380

N. diseases: 123; N. variants: 9
Disease: HIV-1 infection ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.020 GeneticVariation disease BEFREE CR2 genetic variants are associated with susceptibility to systemic lupus erythematosus as well as to HIV-1 infection. 31634193 2020
CUI: C2363741
Disease: HIV-1 infection
HIV-1 infection 		0.020 Biomarker disease BEFREE B-cell dysfunction was examined in patients with HIV-1 infection (n = 30) who had received ART for a median time of 9.25 years (range: 1.3-21.7) by assessing proportions of CD21 B cells (a marker of B-cell exhaustion) and proportions of tumor necrosis factor-related apoptosis-inducing ligand or B and T lymphocyte attenuator B cells, and serum levels of immunoglobulin free light chains (markers of B-cell hyperactivation). 26914910 2016